Possibilities of endoscopic endonasal transsphenoidal surgery in treatment of growth-hormone pituitary adenomas

Abstract

Pituitary adenomas are one of the most common primary central nervous system tumours and have an estimated prevalence of 17%.  Management of hormone-secreting pituitary adenomas involves a multidisciplinary approach that can incorporate surgical, medical, and/or radiation therapies. Acromegaly is a rare, chronic disorder that mostly results from growth hormone (GH)-secreting pituitary adenoma. We analyzed the outcomes of surgical treatment for growth hormone (GH) pituitary adenomas based on 28 cases and determine factors that lead to biochemical remission.