Abstract
The surgical treatment of the lumbar disc hernia is, in same cases, followed by complications which are included in a clinical syndrome named failed back surgery syndrome (FBSS). Lumbar fibrosis is responsible in 24% of cases of FBSS. We review the literature concerning this subject. Many studies looked for methods to prevent this complication, with moderate effectiveness. ADCON gel, which raised great expectations - produced no positive effect in patients who underwent microdiscectomy, and is now out of use. Currently, the results of experimental studies with local Mitomycin C and preoperative extenal radiotherapy (7 Gy) are promising and allow us performing clinical studies.
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